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In further embodiments, the invention encompasses a method of modulating stem cell differentiation by contacting a stem cell expressing NNMT with one or more cations chosen from 1c, 1f, 1l, 1m, 2j, 2k, 2l, 2m, 2aa, 1c, 1f, 1l, 1m, 2j, 2k, 2l, 2m, and 2aa

PTSD in women is associated with a block in conversion of progesterone to the GABAergic neurosteroids allopregnanolone and pregnanolone measured in plasma

Pro-vitamin A/C, histone enzyme D, acidic ceramidase, transitional endoplasmic reticulum ATPase, cytoplasmic dynamin 1, whose expression was elevated, and tripeptidyl peptidase 1 were among the lysosomal functions-related proteins discovered among these (Acera et al., 2022)

Funct Integr Genomics 11:293305

5.4 Other modulators of cGAS-STING signaling pathway Additional modulators primarily target the downstream signaling of cGAS-STING signaling pathway, and some of them have been studied in animal models